Posted on October 20, 2022
Abstract In ethnopharmacological research, many field assessment tools exist. Yet, these miss that critical point of how to really determine which species merit the costly lab studies, e.g., evaluation of traditional use via pharmacological assays and isolation of bioactive secondary metabolites. This gap can be filled with the introduction of a new tool for literature assessment: the Degrees of Publication (DoPs). In this study, its application is illustrated through an extensive bibliographic assessment of 16 medicinal plant species that were recently identified in the Greater Mpigi region of Uganda as being frequently used by local traditional healers in the treatment...
Posted on October 20, 2022
Abstract Plants are commonly used during the antenatal stage in pregnancy to manage different ailments in Africa. In Uganda, both medicinal and food plants are used to handle common pregnancy related conditions. An ethnobotanical survey was conducted in Iganga district, eastern Uganda. Seven traditional birth attendants (TBA) and 46 mothers were interviewed. Data was collected using structured questionnaires and household interviews. The TBAs were identified using snowball sampling. A total of 33 plant species, belonging to 23 families were documented. Out of these, the pregnant mothers used 45.5 % as both food and medicine. The most frequently used plant life...
Posted on October 20, 2022
Abstract Background There are high mortality and morbidity rates due to poisonous snakebites globally with sub-Saharan Africa having some of the highest cases. However, traditional medicine practitioners (TMP) have been treating snakebites in Uganda for long despite the fact that few studies have been conducted to document such vital and rich indigenous traditional knowledge before it is lost. This study aimed to document the medicinal plant species used by experienced TMP in treating snakebite envenomation in selected post-conflict parts of Uganda. An ethnopharmacological survey was conducted in Kitgum, Serere, Kaberamaido and Kaabong districts in Uganda. Twenty-seven TMP with expertise in...
Posted on October 20, 2022
Abstract: Aims: To inventory the wild plant species used both as food and medicine and how they are used in Panyago Sub County, Nebbi district. Study Design: Ethnobotanical study. Place and Duration of Study: The villages of Kaal, Padoch South, Nyakaduli and Pacer South, Panyango Sub County, Jonam County in Nebbi district, between May and July 2011. Methodology: Data were collected from the local people using questionnaires, Focus Group Discussions (FGD’s) and field observations. Both purposeful sampling and simple random sampling methods were used to obtain the required information. Triangulation was achieved by combining the different data collection techniques and...
Posted on October 20, 2022
Abstract In Uganda, malaria has been ranked as a leading cause of morbidity and mortality with Apac District having one of the highest transmission rates. The objective of this study was to assess the use of medicinal plants in preventing and treating malaria and to determine the traditional concept of malaria in Cegere Sub-County, Apac. A snowball sampling method was used to work through a network of informants. Ninety respondents, including traditional healers, were interviewed using focus group discussions and questionnaires. Twenty plant species from 15 families were used for preventing and treating malaria. Most of the plants were herbs...
Posted on October 20, 2022
Abstract Antibiotic resistance poses one of the greatest threats to global health today; conventional drug therapies are becoming increasingly inefficacious and limited. We identified 16 medicinal plant species used by traditional healers for the treatment of infectious and inflammatory diseases in the Greater Mpigi region of Uganda. Extracts were evaluated for their ability to inhibit growth of clinical isolates of multidrug-resistant ESKAPE pathogens. Extracts were also screened for quorum quenching activity against S. aureus, including direct protein output assessment (δ-toxin), and cytotoxicity against human keratinocytes (HaCaT). Putative matches of compounds were elucidated via LC–FTMS for the best-performing extracts. These were extracts...
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